Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 5727
Gene Symbol: PTCH1
PTCH1
Q13635 patched 1 604 0.398 0.885 1.00 0.500 None 0.942 103 6 1994 2020
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.100 None 1.000 10 2 2000 2020
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1193 0.320 0.923 1.00 0.070 None 0.857 7 2 2002 2020
Entrez Id: 4314
Gene Symbol: MMP3
MMP3
P08254 matrix metallopeptidase 3 Enzyme 473 0.408 0.885 5.7E-15 0.030 None 1.000 3 0 1994 2020
Entrez Id: 4321
Gene Symbol: MMP12
MMP12
P39900 matrix metallopeptidase 12 Enzyme 216 0.484 0.885 0.020 None 1.000 2 0 2000 2020
Entrez Id: 51548
Gene Symbol: SIRT6
SIRT6
Q8N6T7 sirtuin 6 Epigenetic regulator 195 0.496 0.846 3.9E-02 0.010 None 1.000 1 0 2020 2020
Entrez Id: 1747
Gene Symbol: DLX3
DLX3
O60479 distal-less homeobox 3 Transcription factor 67 0.601 0.692 2.6E-03 0.010 None 1.000 1 0 2020 2020
Entrez Id: 503694
Gene Symbol: DEFB108A
DEFB108A
A8MXU0 defensin beta 108A 1 1.000 0.038 0.010 None 1.000 1 0 2020 2020
Entrez Id: 6777
Gene Symbol: STAT5B
STAT5B
P51692 signal transducer and activator of transcription 5B Nucleic acid binding 357 0.442 0.808 1.00 0.010 None < 0.001 1 0 2020 2020
Entrez Id: 6778
Gene Symbol: STAT6
STAT6
P42226 signal transducer and activator of transcription 6 Nucleic acid binding 281 0.475 0.808 0.99 0.010 None < 0.001 1 0 2020 2020
Entrez Id: 6776
Gene Symbol: STAT5A
STAT5A
P42229 signal transducer and activator of transcription 5A Nucleic acid binding 318 0.445 0.808 1.00 0.010 None < 0.001 1 0 2020 2020
Entrez Id: 503837
Gene Symbol: DEFB108C
DEFB108C
A8MXU0 defensin beta 108C 1 1.000 0.038 0.010 None 1.000 1 0 2020 2020
Entrez Id: 245911
Gene Symbol: DEFB108B
DEFB108B
Q8NET1 defensin beta 108B 1 1.000 0.038 1.6E-03 0.010 None 1.000 1 0 2020 2020
Entrez Id: 407040
Gene Symbol: MIR34A
MIR34A
microRNA 34a 428 0.421 0.846 0.010 None 1.000 1 0 2020 2020
Entrez Id: 165
Gene Symbol: AEBP1
AEBP1
Q8IUX7 AE binding protein 1 69 0.631 0.654 7.3E-11 0.010 None 1.000 1 0 2020 2020
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.500 None 0.938 80 5 1992 2019
Entrez Id: 2735
Gene Symbol: GLI1
GLI1
P08151 GLI family zinc finger 1 369 0.431 0.846 7.7E-14 0.100 None 0.972 36 2 1997 2019
Entrez Id: 6608
Gene Symbol: SMO
SMO
Q99835 smoothened, frizzled class receptor G-protein coupled receptor 215 0.489 0.731 4.3E-07 0.700 None 0.955 22 6 1998 2019
Entrez Id: 2736
Gene Symbol: GLI2
GLI2
P10070 GLI family zinc finger 2 351 0.446 0.846 0.97 0.400 None 1.000 17 0 2000 2019
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1234 0.314 0.962 1.00 0.100 None 0.857 14 0 1999 2019
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
P35222 catenin beta 1 1368 0.303 0.885 1.00 0.100 None 1.000 13 1 2002 2019
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 2367 0.248 0.962 0.32 0.390 None 0.900 10 1 2001 2019
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor Kinase 1394 0.295 0.885 0.37 0.100 None 0.900 10 0 1995 2019
Entrez Id: 8314
Gene Symbol: BAP1
BAP1
Q92560 BRCA1 associated protein 1 Enzyme 299 0.454 0.731 0.99 0.460 None 1.000 7 1 2015 2019
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1511 0.292 0.923 1.00 0.450 None 1.000 6 0 2009 2019